Advances in Vaccines for Controlling Foodborne Salmonella spp. in Poultry

Abstract

Salmonellosis is a zoonotic disease caused by the gram-negative enteric bacterium Salmonella. They are not restricted to particular host species, and their epidemiology can therefore be complex. Most are able to colonize the alimentary tract of animals without production of disease; more than 2500 serotypes have been described, mostly belonging to the species S. enterica. Infections with broad-host-range serovars, such as S. typhimurium and S. enteritidis, result in asymptomatic carriers that play a major role in Salmonella propagation in poultry and hence in food contamination. Vaccination that is the most practical and effective method to control salmonellosis in poultry, especially in breeders and layers, is well documented for the decline of salmonellosis in poultry products in the United Kingdom (O’Brien 2013).