Renal papillary necrosis

Abstract

The renal papillary necrosis is a rarely observable disease that usually presents itself as a complication of another disease. It is a focal or total necrosis of the papilla and adjacent areas of the renal medulla. You can manifest itself at any or all mark cones of one or both kidneys. As predisposing underlying diseases are described: diabetes mellitus, bacterial and mycotic (renal) infections, use of analgesics, especially NSAIDs, sickle cell disease, alcohol abuse. The disease usually occurs in adulthood. In childhood pyelonephritis is the most common cause. Mostly it is a multifunctional event. Pathologically are microvascular changes (thrombotic and necrotic closures of the capillaries), resulting in a papillary ischemia due to a reduction in the blood supply. Renal papillary necrosis and underlying diseases requiring a comprehensive diagnosis. The therapy is primarily the renal papillary necrosis. The prognosis depends on the severity of the underlying disease and this disease.