Abstract
Key Features: Human skin is capable of retinoid metabolism and storage. Human epidermis expresses retinoic acid receptors (RAR-γ > RAR-α) and retinoic X receptors (RXR-α > RXR-β) and is therefore responsive to retinoid treatment. Nonaromatic, monoaromatic and polyaro-matic retinoid derivatives are used for systemic and topical treatment of various skin disorders. Systemic retinoids are highly teratogenic and application of topical retinoids should be avoided altogether during pregnancy. Country-specific approvals and recommendations have to be consulted before applying retinoid containing drugs. © 2010 Springer-Verlag Berlin Heidelberg.
Cite
CITATION STYLE
Baron, J. M. (2010). Retinoid pharmacology. In Therapy of Skin Diseases: A Worldwide Perspective on Therapeutic Approaches and Their Molecular Basis (pp. 77–85). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-78814-0_8
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