Role of Nitric Oxide in Neurological Disorders

Abstract

Although one of the simplest biological molecules in nature, nitric oxide (NO) has found its way into nearly every phase of biology and medicine, ranging from its role as a critical endogenous regulator of blood flow and thrombosis to a principal neurotransmitter mediating erectile function as well as a major pathophysiological mediator of inflammation and host defense. Role of NO in physiology, pathology, pharmacology andhuman therapeutics has been described in detail in a special report on the topic (Jain 2012).