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Ratiometric two-photon fluorescent probe for: In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication

Chemical Communications (2019) 55(76) 11358-11361
DOI: 10.1039/c9cc05759e
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Abstract

We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.

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Jiang, A., Chen, G., Xu, J., Liu, Y., Zhao, G., Liu, Z., … James, T. D. (2019). Ratiometric two-photon fluorescent probe for: In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication. Chemical Communications, 55(76), 11358–11361. https://doi.org/10.1039/c9cc05759e

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