In the developing cerebellum, granule cells migrate from their birth place to their final destination. The active translocation of granule cells is essential for the formation of cerebellar cortical layers and their proper differentiation. This chapter will review (1) how granule cells migrate from their origin to their resident destinations in the developing cerebellum, (2) the mechanisms involved in normal and abnormal migration of granule cells, and (3) the mechanisms underlying the differentiation of granule cells.
CITATION STYLE
Komuro, Y., Fahrion, J. K., Foote, K. D., Fenner, K. B., Kumada, T., Ohno, N., & Komuro, H. (2013). Granule cell migration and differentiation. In Handbook of the Cerebellum and Cerebellar Disorders (pp. 107–126). Springer Netherlands. https://doi.org/10.1007/978-94-007-1333-8_7
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