Synthesis of glycerol mono-laurate from lauric acid and glycerol for food antibacterial additive

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Abstract

Synthesis of glycerol mono-laurate (GML) has been performed using esterification reaction of glycerol and lauric acid. The reaction was performed at the condition of temperature of 120-140 °C within 7 hour, variation of molar ratio of glycerol - lauric acid, and was using heterogeneous catalyst of zeolist Y. Without catalyst dealumination the maximum acid conversion was 78%, with GML contained in the sample was 38.6%, and it was obtained at the reaction condition of 140 oC, 15wt% catalyst, and 8:1 molar ratio of glycerol - lauric acid. At the same condition, using dealuminated catalyst, the maximum acid conversion was increased up to 98%, with GML contained in the sample was 50.4%. The GML antibacterial activity was examined. It was observed that the GML has antibacterial activity against gram positive bacterial such as B. cereus and S. aureus.

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Setianto, W. B., Wibowo, T. Y., Yohanes, H., Illaningtyas, F., & Anggoro, D. D. (2017). Synthesis of glycerol mono-laurate from lauric acid and glycerol for food antibacterial additive. In IOP Conference Series: Earth and Environmental Science (Vol. 65). Institute of Physics Publishing. https://doi.org/10.1088/1755-1315/65/1/012046

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