Microparticulate hot melt pallets technology: a review

Abstract

Recent advances in novel drug delivery (NDDS) aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance. Depending upon functionality, it is possible to design different dosages forms which fulfill the therapeutic needs of the patient with improved bioavailability of poorly water soluble drugs, taste masking and preparation of oral dispersible tablets, MUPS and multiple unit formulations. The hot-melt technology is one of the most commonly used method,  is devoid of solvent use, solvent disposal, solvent evaporation and solvent treatment is not required. Keywords: Multiple Unit Pallet Systems, Lipid, Solubility, Hot-Melt Technology, Bioavailability, Absorption of Drug.