EVALUATING THE CAUSES FOR REJECTION OF POTENTIAL LIVE-RENAL DONORS: SINGLE CENTER EXPERIENCE

Abstract

Objective: Renal transplantation provides better outcomes for end stage renal disease patients in comparison to dialysis. Living kidney donation provides better long-term patient and graft survival compared to deceased-donor transplantations. In the long term, complications such as mild proteinuria, an increase in blood pressure, preeclampsia, end stage renal disease and mortality are the main problems for donors. In this study, we aimed to evaluate the causes of kidney donor rejections in our hospital. Material and Method: The medical files of individuals presented as donor candidates were retrospectively examined. Screening tests, cross match test, tissue typing, routine evaluation of cardiologic system, respiratory system, psychiatric condition and cancer screenings, if necessary, were performed as part of the donor candidate work-up. Data was expressed as mean±SD. Results: Two hundred and forty five individuals presented themselves as donor candidates in our hospital. Of these, 118 patients could not be donors. Of these 118 individuals, 21 potential donors were rejected donor despite completing all evaluations. The main causes for rejection of 97 individuals were hypertension, diabetes mellitus-obesity and asymmetry in glomerular filtration rate/parenchymal abnormalities. In addition, we diagnosed cancer in 5 potential donors. Conclusion: Potential kidney donor evaluation is of paramount importance in order to minimize possible risks.