Estudio comparativo de tres técnicas de hemodiálisis: AFB-K, Hemodiafiltración y Hemodiálisis de alto flujo

Abstract

Research in nephrology seeks to find increasingly efficient extrarenal purification techniques. The dialysis technique of potassium-profiled acetatefree biofiltration offers better tolerance and reduces the risk of arrhythmias. Our aim was to compare this technique with high-flow haemodialysis and with haemodiafiltration in order to ascertain which dialysis treatment is the most suitable for each patient. A prospective, controlled cross study in which the same patients were their own control group. The choice of patients and technique was random, with the patients undergoing 13 consecutive sessions of dialysis with each of the techniques being studied. Throughout the study, the following dialysis parameters were kept constant: duration of the session, flow, calibre of the needs and dose of heparin. Fifteen days after starting each period, patients were given an electrocardiogram and blood test (all pre and post dialysis). With the biofiltration and haemodiafiltration techniques the bicarbonate value is more physiological. With biofiltration and high-flow haemodialysis a better correction of the acid-base balance is achieved. As regards sodium value, there are small differences in the three techniques, always within the physiological interval. In haemodiafiltration, episodes of arrhythmia increased. The three methods have shown correct dialysis efficiency, tolerance and cardiovascular stability.