The Composition of Dialysis Fluid

Abstract

Kolff (1) anticipated most of the problems that have been encountered in formulating a suitable dialysis fluid for haemodialysis. After many trials he advocated a low sodium, high potassium fluid (Table 1). The major problem was the high pH of the solution and the presence of bicarbonate which affected the solubility of calcium salts. Kolff attempted to adjust pH by bubbling CO2 into the dialysis fluid. He finally used tap water containing calcium 1.0 mmol/l and gave calcium gluconate intravenously post-dialysis. To avoid haemolysis, dextrose monohydrate was added.