In vitro cyclooxygenase activity assay in tissue homogenates.

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Abstract

The use of in vitro cyclooxygenase (COX) activity assays has been particularly useful for comparing the effect of different drugs on COX activity in different tissues. In addition, this assay is relatively quick, cheap, and a large number of samples can be tested at the same time. However, one limitation of this assay is the fact that it does not discriminate between the activities of different COX isoforms.

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Ayoub, S. S. (2010). In vitro cyclooxygenase activity assay in tissue homogenates. Methods in Molecular Biology (Clifton, N.J.), 644, 117–120. https://doi.org/10.1007/978-1-59745-364-6_9

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