Intrinsic Antibiotic Resistance Mechanism in Bacteria

Abstract

Bacteria are unicellular microorganisms and they have very simple structure, all their functions are controlled by a single cell only. Despite of this, they are as complicated as simple, their complexity is residing in their genomic plasticity. They can adapt very gently in any harsh environmental conditions by tuning up their genomic plasticity accordingly. In this regard, bacteria have evolved several resistance mechanisms against the currently available antibiotics. These resistance mechanisms can be acquired or intrinsic. Hence, in this chapter, we have recapitulated the most widely existing intrinsic resistance mechanism of bacteria.