Preliminary safety estimate of cosmetic anti-age creams with chokeberry extract, using in vivo bioengineering techniques

Abstract

Potential of anti-age cosmetic line, day and night creams were evaluated using noninvasive measure- ments of the appropriate skin biophysical parameters in a 24-h in vivo study under occlusion. Thirty- one healthy female volunteers were involved in the study. Electrical capacitance (EC), transepidermal water loss (TEWL), erythema index (EI) were evaluated. The preliminary safety profile of the investi- gated creams with natural origin ingredients based on obtained results can be considered satisfactory. The stated samples did not cause the change in the measured biophysical parameters-TEWL and EI, while they increased EC i.e. stratum corneum hydration. These results suggest that chokeberry ex- tract and other natural ingredients could exert beneficial effects and has potential on aged skin thereby slowing down the appearance of wrinkles and their existing alleviation, and they could be considered preferable in the cosmetic products intended for the treatment of aged skin.