High-LET-emitting radionuclides for cancer therapy

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Abstract

During the last 15 years, alpha-particle emitting radionuclides have been investigated as a possible new class of radionuclides for targeted therapy. Alpha-particles can deposit DNA damaging energy 100 to 1,000 times greater than beta-particles. In this chapter, the background and clinical experiences of targeted alpha-particle radioimmunotherapy use are discussed. © 2008 Springer Science+Business Media B.V.

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Sgouros, G. (2008). High-LET-emitting radionuclides for cancer therapy. In Targeted Radionuclide Tumor Therapy: Biological Aspects (pp. 175–180). Springer Netherlands. https://doi.org/10.1007/978-1-4020-8696-0_9

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