Copper(I)-Catalyzed Desulfinative Carboxylation of Sodium Sulfinates using Carbon Dioxide

Abstract

A copper(I)-catalyzed desulfinative carboxylation of sodium sulfinates using carbon dioxide has been developed. This reaction showed wide functional group tolerance. A series of sodium aryl- and alkenylsulfinates could be converted into the corresponding carboxylic acids in good to excellent yields. Additionally, the reaction mechanism was studied by in situ NMR analysis and isotopic labeling experiments.