The solubility of Microcrystalline cellulose in sodium hydroxide solution is inconsistent with international specifications

1Citations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

Microcrystalline cellulose (MCC) is used globally as an inactive ingredient in food and nutraceutical products and is commonly used as a food additive. To confirm the conformity of MCC to the solubility requirements stipulated in international specifications, the solubilities of commercially available MCC products were tested in sodium hydroxide (NaOH) solution. All of the samples were insoluble in NaOH solution, which is inconsistent with the descriptions provided in international specifications. We also prepared celluloses with different degree of polymerization (DP) values by acid hydrolysis. Celluloses with lower DP were prepared using a three-step process, and their solubilities were tested in NaOH solution. These celluloses were found to be insoluble, which is inconsistent with the descriptions provided in international specifications. The present study suggests that the descriptions of the solubility of the celluloses in NaOH solution found in the current international specifications should be revised.

Cite

CITATION STYLE

APA

Kodama, H., Tamura, Y., Kamei, I., Sato, K., & Akiyama, H. (2017). The solubility of Microcrystalline cellulose in sodium hydroxide solution is inconsistent with international specifications. Biological and Pharmaceutical Bulletin, 40(1), 68–72. https://doi.org/10.1248/bpb.b16-00600

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free