Bioanalytical assays LC-MS/MS

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Abstract

Powerful analytical techniques are one key requirement for successful drug research and development. The concentration of drugs, prodrugs, and metabolites has to be determined in very diverse matrices such as plasma (blood), urine, feces, and also in different organ tissues (depending on the nature of the drug and on the targeted organs).

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Krause, J., & Schmidt, R. (2013). Bioanalytical assays LC-MS/MS. In Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays, Second Edition (pp. 853–868). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-25240-2_35

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