The total artificial heart in pediatrics: Outcomes in an evolving field

10Citations
Citations of this article
15Readers
Mendeley users who have this article in their library.

Abstract

Background: The use of the SynCardia temporary total artificial heart (TAH-t) in adults has increased with time. The development of the smaller, 50 cc TAH-t has expanded the potential applications of the device in children. We sought to describe the evolving use of the TAH-t over time and describe outcomes in the current era. Methods: The SynCardia database was queried to identify all pediatric patients =18 years of age implanted with the device between December 1985 and October 2019. Patient demographics, clinical outcome and support characteristics collected. Results: Fifty-one children were supported, 36 with the 70 cc TAH-t and 15 with the 50 cc TAH-t with a total support time of 6,243 days. The number of implants has increased with time (19 between 2015 and 2019). A total of 13 patients have been converted to Freedom Driver support, seven 50 cc TAH-t and six 70 cc TAH-t. The majority of implants in the last 5 years (15/19, 79%) have been with the 50 cc TAH-t. The most common diagnosis was dilated cardiomyopathy [24 (47%)] and the average age at the time of implant was 16±2 years old. Overall survival for the patient cohort was 71%. Conclusions: The use of the SynCardia TAH-t to support children with end-stage heart failure has increased over time. Clinical outcomes with both the 50 cc and 70 cc TAH-t are similar to reported outcomes in adults who require TAH-t or other methods of biventricular support.

References Powered by Scopus

Cardiac replacement with a total artificial heart as a bridge to transplantation

450Citations
N/AReaders
Get full text

The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Twenty-second pediatric heart transplantation report – 2019; Focus theme: Donor and recipient size match

182Citations
N/AReaders
Get full text

Interagency registry for mechanically assisted circulatory support report on the total artificial heart

101Citations
N/AReaders
Get full text

Cited by Powered by Scopus

ISHLT consensus statement for the selection and management of pediatric and congenital heart disease patients on ventricular assist devices Endorsed by the American Heart Association

50Citations
N/AReaders
Get full text

Patient and Device Selection in Pediatric MCS: A Review of Current Consensus and Unsettled Questions

7Citations
N/AReaders
Get full text

The use of mechanical assist devices in the pediatric population

7Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Villa, C. R., Moore, R. A., Morales, D. L., & Lorts, A. (2020). The total artificial heart in pediatrics: Outcomes in an evolving field. Annals of Cardiothoracic Surgery, 9(2), 104–109. https://doi.org/10.21037/ACS.2020.02.15

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 3

60%

Researcher 2

40%

Readers' Discipline

Tooltip

Medicine and Dentistry 7

78%

Agricultural and Biological Sciences 1

11%

Materials Science 1

11%

Save time finding and organizing research with Mendeley

Sign up for free