Distinct requirement of RNA polymerase II CTD phosphorylations in budding and fission yeast

Abstract

The "CTD code" links the combinatorial potential of the modifications found on the Rpb1 C-terminal domain (CTD) to the growing group of CTD binding effectors. The genetic dissection of serine 2 and serine 7 function within the CTD in both budding and fission yeast reveals distinct in vivo requirement. © 2012 Landes Bioscience.