Empirical antibiotic treatment for peritoneal dialysis-related peritonitis: Can "one size" fit all?

Abstract

In summary, the choice of empirical antibiotics for the treatment of PD-related peritonitis should be tailor-made and center specific. While the regimen proposed by Barreira and colleagues might be effective in a certain population with low background bacterial resistance, it might not be useful in others. It is obvious that no single empirical antibiotic regimen can "fit" all dialysis programs. Individual dialysis program should take into account the profile of organisms causing peritonitis in their locality and their antibiotic resistance patterns when devising their own empirical antibiotic regimen. Further studies in the form of prospective randomized controlled trials are warranted to evaluate the usefulness of newer generations of antibiotics in the empirical treatment of PD-related peritonitis. Copyright © 2007 International Society for Peritoneal Dialysis.