The human subthalamic nucleus - Knowledge for the understanding of Parkinson's disease

Abstract

The human subthalamic nucleus differs from those of experimental animals, especially rat. In this overview cytological, developmental, and connective discrepancies are enumerated. The main theme is the lack of neuroanatomical prove for the cortico-subthalamic connection in humans. Moreover electrophysiological results show latencies that do not fit in with the assumed distances. © 2010 International Federation for Medical and Biological Engineering.