Brain H2A.Z: The long and the short

Abstract

The role of histone variants and their specific post-translational modifications (PTMs) in the epigenetic regulation of gene expression is still poorly understood. A paper published by Simonet and colleagues in Epigenetics and Chromatin describes a new H2A.Z subtype that is specific for brain and pituitary in the carp and provides additional information about the functional epigenetic complexity of the PTMs associated with histone H2A.Z.See research article: http://www.epigeneticsandchromatin.com/content/6/1/22. © 2013 Ausió; licensee BioMed Central Ltd.