Formation of an amide bond between two amino acids is an energy-requiring reaction. Carboxylic acids do react with amines at elevated temperatures and amides can be produced this way. For instance, ammonium acetate can be converted to acetamide by heating. The...
CITATION STYLE
Bodanszky, M. (1993). Activation and Coupling. In Principles of Peptide Synthesis (pp. 9–61). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-78056-1_2
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