The brain melanocortin system is a primary gateway through which energy balance is controlled. Diano and colleagues report a novel cellular mechanism mediated via reactive oxygen species (ROS) that regulates the activity of these melanocortin neurons in response to energy status, thereby modulating appetitive behavior (Diano et al., 2011). © 2011 Elsevier Inc.
Rochford, J. J., Myers, M. G., & Heisler, L. K. (2011, November 2). Setting the tone: Reactive oxygen species and the control of appetitive melanocortin neurons. Cell Metabolism. Cell Press. https://doi.org/10.1016/j.cmet.2011.10.004