Our understanding of the modulation of proteins has shifted in direction with the discovery of microRNAs (miRs) over twenty years ago. MiRs are now in the "limelight" as these non-coding pieces of RNA (generally ~22 nucleotides long) result in altered translation and function of proteins. Indeed, miRs are now reported to be potential biomarkers of disease. Epithelial K+ channels play many roles in electrolyte and fluid homeostasis of the human body and have been suggested to be therapeutic targets of disease. Interestingly, the role of miRs in modulating K+ channels of epithelial tissues is only emerging now. This minireview focuses on recent novel findings into the role of miRs in the regulation of K+ channels of epithelia.
CITATION STYLE
Pilmore, E., & Hamilton, K. L. (2015). The role of MicroRNAs in the regulation of K+ Channels in Epithelial Tissue. Frontiers in Physiology. Frontiers Research Foundation. https://doi.org/10.3389/fphys.2015.00352
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