Background: Metastatic renal cell carcinoma (RCC) presents a therapeutic challenge for clinicians because of the unpredictable clinical course, resistance to chemotherapy or radiotherapy and the limited response to immunotherapy.Patients and Methods: We report a case of a 62-year-old woman who underwent nephrectomy for T4N0 RCC, clear cell type, Fuhrman grade 3/4 in 1999. The patinet subsequently had multiple tumor recurrences.Results: The patient underwent eight metastasectomies, including multiple partial left nephrectomies, right adrenalectomy, a complete left nephrectomy, and distal pancreatectomy. She remains well and tumor free 12 years after initial diagnosis.Conclusion: Repeated resections after initial metastasectomy can be carried out safely and provide long-term survival in selected patients with recurrent metastasis from RCC. The findings from our case indicate that close follow-up for the early detection of recurrence and complete resection of metastases can improve the results after repeated resection. © 2011 Wang et al; licensee BioMed Central Ltd.
CITATION STYLE
Wang, J., Talmon, G. A., Feloney, M., & Morris, M. C. (2011). Twelve-year survival after multiple recurrences and repeated metastasectomies for renal cell Carcinoma. World Journal of Surgical Oncology, 9. https://doi.org/10.1186/1477-7819-9-155
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