Abstract
Three hitherto unknown taxane diterpenoids, namely baccatin VIII (1), baccatin IX (2), and baccatin X (3), along with 10 known analogues were isolated from an ethanolic extract of the twigs and leaves of Taxus yunnanensis. The new structures were characterized based on extensive spectroscopic analysis. Compounds 1 and 2 were tested for their in vitro cytotoxicity against five human tumor cell lines, and 1 exhibited inhibitory effects on HL-60 and MCF-7, with IC50 values of 3.44 and 9.67 μM, respectively.
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Hai, P., Wen, S. Z., Li, Y., Gao, Y., Jiang, X. J., & Wang, F. (2014). New Taxane Diterpenoids from Taxus yunnanensis. Natural Products and Bioprospecting, 4(1), 47–51. https://doi.org/10.1007/s13659-014-0003-9
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