Single-sided coil configuration for magnetic particle imaging

Abstract

Magnetic particle imaging (MPI) is a tomographic imaging technique, which allows for measuring the spatial distribution of magnetic nanoparticles. It potentially achieves high sensitivity, high spatial resolution and high imaging speed. The first implemented MPI scanner system presented by Gleich and Weizenecker is a closed system with a small bore which fits only small specimens. In order to exploit other system geometries accommodating larger objects, Sattel et al presented a new, so-called single-sided scanner geometry where the size of the specimen is no longer relevant, although penetration depth is limited. The feasibility of this new concept was shown by manufacturing an experimental setup. In this work, the imaging chain is simulated from the generated magnetic fields to the nanoparticle magnetization and the induced receive signal. Measurement and simulation results are compared and deficiencies of the implemented system are depicted. © 2009 Springer-Verlag.