AB1097 FEATURES OF THE COURSE AND CLINICAL AND DEMOGRAPHIC CHARACTERISTICS OF PATIENTS WITH RHEUMATOID ARTHRITIS WHO UNDERWENT COVID-19

Abstract

Background: COVID-19 remains a serious problem almost two years later, despite the ongoing active search for effective tools to control it. To date, it is known that COVID-19 not only proceeds as an acute respiratory illness, but also leads to a systemic infammatory response and hypercoagulability through activation of both the innate and adaptive immune systems. Patients with rheumatic and musculoskeletal diseases appear to be more vulnerable to the development of severe forms of COVID-19 due to the impaired immune response associated with RMD. In addition, immunosuppressants prescribed to control RMD increase the risk of infections. And fnally, RMD is often combined with comorbid conditions from the group of risk factors for severe forms of COVID-19 such as arterial hypertension, diabetes mellitus and obesity. Objective(s): to characterize the features of the course of COVID-19 in patients with rheumatoid arthritis. Method(s): We studied the material of questionnaires flled out by patients of the hospital of the V.A. Nasonova Research Institute of Rheumatology who underwent COVID-19, verifed by RT-PCR to SARS-CoV-2 RNA, for the period from 05/15/2020 to 12/15/2021. The information was supplemented with data from discharge reports after inpatient treatment of COVID-19. Statistica software (version 12) was used for statistical processing. The results of the correlation analysis were considered reliable at p