Therapy of adult acute leukemia with daunorubicin and L‐asparaginase

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Abstract

Fifty‐four adults with acute leukemia resistant to other therapies received treatment with Daunorubicin and L‐asparaginase. Seventeen (31%) achieved complete remission. The complete remission rate was higher among the 31 patients receiving simultaneous therapy than among the 23 patients receiving sequential therapy (42% vs. 17%). Patients with acute lymphocytic leukemia had a higher remission rate than patients with acute myelogenous leukemia (38% vs. 20%). The median duration of complete remission was only 12 weeks, and the median duration of survival for responders was 30 weeks. Copyright © 1974 American Cancer Society

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Bodey, G. P., Hewlett, J. S., Coltman, C. A., Rodriguez, V., & Freireich, E. J. (1974). Therapy of adult acute leukemia with daunorubicin and L‐asparaginase. Cancer, 33(3), 626–630. https://doi.org/10.1002/1097-0142(197403)33:3<626::AID-CNCR2820330306>3.0.CO;2-5

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