Abstract
Two novel triterpene sulfates have been isolated from Fusarium compactum by bioactivity-directed fractionation using an assay which measures the inhibition of proteolytic activity of rhinovirus 3C protease on a fluorogenic peptide substrate. The compounds were purified by countercurrent and reverse phase chromatographies. NMR, MS, UV and IR studies revealed two triterpene sulfates, uncommon metabolites of terrestrial fungi.
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CITATION STYLE
Brill, G. M., Kati, W. M., Montgomery, D., Karwowski, J. P., Humphrey, P. E., Jackson, M., … McAlpine, J. B. (1996). Novel triterpene sulfates from Fusarium compactum using a rhinovirus 3C protease inhibitor screen. Journal of Antibiotics, 49(6), 541–546. https://doi.org/10.7164/antibiotics.49.541
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