Genetics and sychosis

Abstract

SUMMARY Genetic research into sychotic disorders is advancing ra idly. On the basis of general evidence for genetic influences from family, twin and ado tion studies, molecular genetic studies, articularly genome-wide association studies (GWAS), are identifying a range of common genetic risk factors that each have a small effect on risk, while certain chromosomal co y number variants (CNVs) are rarer, but have a larger effect on risk. There is also evidence for artial overla of genetic influences among sychotic disorders and with non-sychotic disorders. This brief article summarises the main themes, current findings and otential future directions.