Angiolymphoid hyperplasia with eosinophilia

Abstract

BACKGROUND: Angiolymphoid hyperplasia with eosinophilia is a rare benign vascular proliferation of uncertain etiology. The most frequent topography is in the head and neck, with predilection at the preauricular level. The lesions are reddish-brown papular in appearance from 0.5 to 3 cm in diameter. They can be asymptomatic or present pruritus, pain or bleeding. Histologically, vessels with proliferation of epithelioid endothelial cells with diffuse lymphocytic infiltrate and eosinophils are found in the dermis. The differential diagnosis must include various diseases, especially Kimura’s disease and pyogenic granuloma. It is a dermatosis of benign and chronic evolution, with a tendency to recur in 30-50%. Surgical excision with free margins is the treatment of choice; however, recurrence of 33% is reported. CLINICAL CASE: A 59-year-old male patient with angiolymphoid hyperplasia with eosinophilia at the right preauricular level with adequate response to cryotherapy. CONCLUSION: Angiolymphoid hyperplasia with eosinophilia is a rare disease, in which multiple treatment have been tried.