Fatal multisystem infl ammatory syndrome in adult after sars-cov-2 natural infection and covid-19 vaccination

Abstract

We describe a fatal case of multisystem infl ammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical fi ndings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood.