Abstract
The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities. Cytogenetic study of the tumor cells disclosed several abnormalities: 46, XX, 7q-/46, XX, -2, 4p-, 7p-, +15/46, XX. Some aspects about genetics of glial neoplasms are discussed.
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CITATION STYLE
Arruda, W. O., Clemente, R. S., Ramina, R., Pedrozo, A. A., Pilotto, R. F., Pinto Júnior, W., & Bleggi-Torres, L. F. (1995). Familial glioblastoma. Arquivos de Neuro-Psiquiatria, 53(2), 312–317. https://doi.org/10.1590/S0004-282X1995000200025
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