Macrocyclic Schiff base complexes of tin(II) and lead(II): Synthesis, spectroscopic characterization, microbial properties and antifertility effects

Abstract

The complexes of tetradentate macrocyclic Schiff base ligands L 1 and L2 with tin(II) and lead(II) metals have been synthesized by the template condensation of 1,10-phenanthroline-2,9- dicarboxaldehyde, 1,2-dibromoethane and 2,3-diamino-1,4-napththoquinone or phenylhydrazine in ethanolic medium. The complexes were characterized by physico-chemical and spectroscopic methods. An octahedral geometry has been suggested for the resulting complexes. In order to evaluate the antifungal and antibacterial activity, the complexes have been screened against a number of pathogenic fungi such as Fusarium oxysporium, Aspergillus niger and Alternaria alternata and bacteria such as Pseudomonas cepacicola, Escherichia coli (-) and Staphylococcus aureus. The results are compared with the activity of the standard pesticides Bavistin and Streptomycin. The sterilizing power on male albino rats has been listed and discussed with the positive findings.