A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF PUNARNAVA MOOL CHURNA AND BHUMYAMALAKI PANCHANGA CHURNA IN PHYSIOLOGICAL JAUNDICE

Abstract

Neonatal jaundice is one of the most common problem found in infants. The present study being exploratory in nature reports the intervention of Punarnava (Boerhavia diffusa) and Bhumyamalaki (Phyllanthus niruri) for managing physiological jaundice. It can be correlated with KoshthaashritaKamala of Ayurvedic texts. In the present study 90 healthy newborns with yellowish tinge and increased Total serum bilirubin (TSB) were selected and randomly divided into 3 groups (30 patients in each group), out of which 8 patients (4 patients from each group B and C) were dropped out. In Group A, patients were treated with Punarnava mool churna and in group B patients were treated with Bhumyamalaki panchanga churna while group C was untreated group. Both drugs were given in dose of 60 mg/kg/day, bid, orally after feed with madhu for 15 days. There were 3 follow ups, 1st after 7 days, 2nd after 15 days and 3rd after 30 days, from the starting of trail. Assessment of the effect of the therapy has been done on the basis of the subjective criteria (according to Kramer's rule) and objective criteria (according to laboratory investigation). Statistical analysis of all three groups show the highly significant results (P < 0.001) however group A shows more significant results than group B and group C and while group B shows more significant results than group C.