A formalism for simulating coupled metabolic and electrophysiological processes is presented. The resulting chemical kinetic and electrophysiological equations are solved numerically to create a cell simulator. Metabolic features of this simulator were adapted from Karyote, a multi-compartment biochemical cell modeling simulator. We present the mathematical formalism and its computational implementation as an integrated electrophysiological-metabolic model. Applications to Geobacter sulfurreducens in the environment and in a fuel cell are discussed. © 2012 Springer Science+Business Media, LLC.
CITATION STYLE
Fontus, M., & Ortoleva, P. (2012). Electrophysiological-metabolic modeling of microbes: Applications in fuel cells and environment analysis. Methods in Molecular Biology, 881, 411–431. https://doi.org/10.1007/978-1-61779-827-6_14
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