Mitochondria play a key role in various modes of cell death. Analysis of mitochondrial dysfunction and the release of proteins from the intermembrane space of mitochondria represent essential tools in cell death investigation. Here we describe how to evaluate release of intermembrane space proteins during apoptosis, alterations in the mitochondrial membrane potential, and oxygen consumption in apoptotic cells.
CITATION STYLE
Gogvadze, V., Orrenius, S., & Zhivotovsky, B. (2015). Analysis of mitochondrial dysfunction during cell death. Methods in Molecular Biology, 1264, 385–393. https://doi.org/10.1007/978-1-4939-2257-4_33
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