History and diagnosis

Abstract

Behçet syndrome, named after Hulusi Behçet, Professor of Dermatology in Istanbul who described the “triple symptom complex” in 1937, is a multisystem, immunologically medicated vasculopathy. The principal clinical features are orogenital aphthous ulceration, uveitis with or without hypopyon and retinal vasculitis, and skin lesions including erythema nodosum and acneiform pustules. Inflammatory arthritis, arterial and venous occlusion and arterial aneurysms, and gastrointestinal and neurological lesions also occur.