Ebola virus and persistent chronic infection: when does replication cease?

Abstract

In this issue of the journal, Shantha et al. report a series of cataract surgeries on survivors of Ebola virus (EBOV) infection. EBOV, originally identified as a new pathogen in 1976 during an outbreak of haemorrhagic fever in Zaire (1), is a highly virulent organism associated with a mortality rate ranging from 50 to nearly 90% [reviewed in (2)].