Vitiligo

Abstract

Vitiligo is a chronic autoimmune disorder characterized by areas of depigmented white patches on the skin due to the loss of melanocytes in the epidermis. Various theories on the pathogenesis of vitiligo exist; however, autoimmune destruction of melanocytes remains the leading hypothesis, followed by intrinsic defects in melanocytes.1 Vitiligo is associated with various autoimmune diseases but is most frequently reported in conjunction with thyroid disorders.2