The Platelet as a Peripheral Model of Serotonergic Function in Child Psychiatry

Abstract

(from the chapter) the possible pharmacologcal relationship between the imipramine binding site in brain and platelet encourages the use of this peripheral "marker" on platelets in clinical research designed to implicate this site in psychiatric disorders and the therapeutic action of TCAs [tricyclic antidepressants] [[superscript]3H]imipramine binding sites / [[superscript]3H]imipramine binding in affective disorders / [[superscript]3H]imipramine binding and serotonin uptake in obsessive-compulsive disorder / platelet imipramine binding in conduct disorder / imipramine binding and serotonin uptake in schizophrenia and autism / imipramine binding and serotonin uptake in enuresis (PsycINFO Database Record (c) 2012 APA, all rights reserved).