Neurologic complications of leukemia

Abstract

Leukemia affects both the central and peripheral nervous systems. Neurological complications are a consequence of both direct leukemic infiltration, as occurs with leukemic meningitis, and complications of either antileukemic treatment (e.g., thrombocytopenic or DIC-related intracranial hemorrhage, steroid myopathy, vinca alkaloid peripheral neuropathy, posterior reversible encephalopathy syndrome, multifocal necrotizing leuko-encephalopathy) or immune compromise (e.g., Herpes zoster shingles or Aspergillus infection). © 2008 Humana Press, Totowa, NJ.