Normal histology of the nasal cavity and application of special techniques.

Abstract

There are three major epithelial types in the nasal mucosa, in addition to numerous accessory structures , some of which are species specific. Without careful and consistent processing of the nose tissue, histopathologic assessment of lesions in the nasal cavity may be compromised. While formalin fixa-tion may be used for routine review ofthe nasal cavity, Bouin's fixation provides better histologic detail and fewer artifacts. Decalcification is not recommended for nasal tissues to be examined by transmission electron microscopy because of the detrimental effect of decalcifyjng solutions on sensory cells.