Cyclodextrin-based supramolecular polymers

Abstract

Supramolecular polymers were prepared by inclusion of a guest in cyclodextrin via a covalent bond. The structures of the supramolecular oligomers and polymers were determined by X-ray studies, NMR measurements, absorption and circular dichroism spectra. The sizes of the supramolecular polymers were determined by vapor pressure osmometry and pulsed-field gradient NMR. Although hydrocinnamoyl β-cyclodextrin formed an intramolecular complex, hydrocinnamoyl α-cyclodextrin formed intermolecular complexes. Cinnamoyl β-cyclodextrin gave a cyclic dimer and cinnamoyl α-cyclodextrin formed a cyclic trimer. α-Cyclodextrin with cinnamic amide at the sec-ondary hydroxyl side gave supramolecular polymers. Formation of the complexes of cyclodextrins with various polymers has also been described. © Springer-Verlag Berlin Heidelberg 2005.