Synthetic biology and genetic manipulation: Risks, promises and responsibilities

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Abstract

As a result of the biotechnological advance, synthetic biology has been applied from the improvement of food to the creation of new organisms. This article investigates, from a bioethical perspective, the benefits, risks and threats to life, arising from the production, manipulation and, especially, the creation of synthesized DNAs that do not exist in nature. Bioethics reports from the White House and the Bioethics Committee of Portugal and Spain contributed to the discussion. The progress of technoscience, without the proper ethical capacity for evaluation, can produce results that compromise the social development, environmental preservation, human dignity, and biosphere life in the future. In this sense, the achievements of synthetic biology have been shown to be ambivalent, because hopes are mixed with threats, with unpredictable results to the diversity of life of the biosphere, which makes prudence the virtue par excellence.

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Rohregger, R., Sganzerla, A., & Simão-Silva, D. P. (2020). Synthetic biology and genetic manipulation: Risks, promises and responsibilities. Ambiente e Sociedade, 23. https://doi.org/10.1590/1809-4422ASOC20180196R3VU2020L4AO

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