Gene gun-mediated delivery of allergen-encoding plasmid DNA has been in focus for many years now as being a needle-free alternative to the protein-based desensitization regimen used in specific immunotherapy. Biolistic immunization with the Helios gene gun has proven to be potent in the induction of antigen-specific CD4+ and CD8+ T cells. Here we describe biolistic vaccination in experimental mouse models of IgE-mediated type I allergy as well as allergen-induced airway inflammation. © 2013 Springer Science+Business Media, LLC.
CITATION STYLE
Raker, V., Maxeiner, J., Reske-Kunz, A. B., & Sudowe, S. (2013). Efficiency of biolistic DNA vaccination in experimental type i allergy. Methods in Molecular Biology, 940, 357–370. https://doi.org/10.1007/978-1-62703-110-3_26
Mendeley helps you to discover research relevant for your work.