Ultrasound-guided methylene blue dye injection for parathyroid localization in the reoperative neck

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Abstract

Background: The goal of this study was to review a single institution's experience using intraoperative ultrasound-guided (ioUSG) methylene blue dye injection for the localization and removal of enlarged parathyroid glands in patients with primary hyperparathyroidism and a history of previous neck surgery. Methods: We performed a retrospective review of nine consecutive patients who underwent reoperative parathyroidectomy using ioUSG methylene blue dye injection. Results: All patients had successful resolution of their hyperparathyroidism, with at least a 50 % decrease in intraoperative parathyroid hormone level after resection. One patient had transient recurrent laryngeal nerve paresis. There were no permanent recurrent laryngeal nerve injuries or cases of permanent hypoparathyroidism. Conclusions: Blue dye injection is a safe and effective method of localizing diseased parathyroid glands in the reoperative neck. © 2013 Société Internationale de Chirurgie.

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Candell, L., Campbell, M. J., Shen, W. T., Gosnell, J. E., Clark, O. H., & Duh, Q. Y. (2014). Ultrasound-guided methylene blue dye injection for parathyroid localization in the reoperative neck. World Journal of Surgery, 38(1), 88–91. https://doi.org/10.1007/s00268-013-2234-z

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